PTGS1 Polyclonal Antibody

Cat.#: 165318

Special Price 174.2 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    PTGS1 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to PTGS1
  • Tested applications
    WB, IHC, IF
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    PTGS1 antibody; COX1 antibody; COX3 antibody; PCOX1 antibody; PES-1 antibody; PGG/HS antibody; PGHS-1 antibody; PGHS1 antibody; PHS1 antibody; PTGHS antibody; prostaglandin G/H synthase 1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human PTGS1 (NP_001258094.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
    IHC 1:100 - 1:200
    IF 1:50 - 1:200
  • Validations

    Western blot - PTGS1 Polyclonal Antibody

    Western blot - PTGS1 Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using PTGS1 antibody at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit ._Exposure time: 15s.

    Immunohistochemistry - PTGS1 Polyclonal Antibody

    Immunohistochemistry - PTGS1 Polyclonal Antibody

    Immunohistochemistry of paraffin-embedded human liver cancer using PTGS1 antibody at dilution of 1:100 (40x lens).

  • Background
    Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"