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Product Name
Human RP2 (GST Tag) recombinant protein
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Description
Acts as a GTPase-activating protein (GAP) involved in trafficking between the Golgi and the ciliary membrane. Involved in localization of proteins, such as NPHP3, to the cilium membrane by inducing hydrolysis of GTP ARL3, leading to the release of UNC119 (or UNC119B). Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor towards ADP-ribosylation factor-like proteins.
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Protein name
Protein XRP2
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Uniprot ID
O75695
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Gene Name
RP2
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human XRP2 (NP_008846.2) (Met 1-Thr 350) was fused with the GST tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human XRP2/GST chimera consists of 575 amino acids and predicts a molecular mass of 66 kDa as estimated in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human XRP2 / RP2 Protein (GST Tag) SDS-PAGE
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