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Product Name
Human APCDD1/DRAPC1 (Fc Tag) recombinant protein
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Description
Negative regulator of the Wnt signaling pathway. Inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin. May act via its interaction with Wnt and LRP proteins. May play a role in colorectal tumorigenesis.
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Protein name
Protein APCDD1
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Protein short names
HTS; EIG180; ETHANOL INDUCED GENE PRODUCT EIG180; HYPOPTRICHOSIS SIMPLEX; AU041258; ADENOMATOSIS POLYPOSIS COLI DOWN-REGULATED 1 PROTEIN; AB023957; APCDD1; DRAPC1; FP7019; HYPT1; B7323; ADENOMATOSIS POLYPOSIS COLI DOWN-REGULATED 1; HHS; ADENOMATOSIS POLYPOSIS COLI DOWN-REGULATED 1 PROTEIN HOMOLOG; PROTEIN APCDD1
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Uniprot ID
Q8J025
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Gene Name
APCDD1; DRAPC1; FP7019
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human APCDD1 (NP_694545.1) (Met1-Gly486) was expressed with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human APCDD1/Fc comprises 701 amino acids and has a predicted molecular mass 79.6 kDa. The apparent molecular mass of the protein is approximately 85.7 kDa in SDS-PAGE under reducing conditions.
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Purity
> 85 % as determined by SDS-PAGE
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Validations
Human APCDD1 Protein (Fc Tag) SDS-PAGE
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