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Product Name
Human PA28A / PSME1 (His Tag) recombinant protein
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Description
Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.
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Protein name
Proteasome activator complex subunit 1
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Protein short names
PA28 ALPHA SUBUNIT; 11S REGULATOR COMPLEX SUBUNIT ALPHA; PROTEASOME (PROSOME; ALPHA; PROTEASOME ACTIVATOR 28 SUBUNIT ALPHA; PSME1; MACROPAIN) 28 SUBUNIT; INTERFERON-GAMMA-INDUCIBLE PROTEIN 5111; 11S REGULATOR COMPLEX ALPHA SUBUNIT; MACROPAIN) ACTIVATOR SUBUNIT 1 (PA28 ALPHA); PROTEASOME ACTIVATOR COMPLEX SUBUNIT 1; 29-KD MCP ACTIVATOR SUBUNIT; REG-ALPHA; INTERFERON GAMMA UP-REGULATED I-5111 PROTEIN; PROTEASE (PROSOME; REGALPHA; AW413925; PA28A; PA28ALPHA; IFI5111; INTERFERON-GAMMA IEF SSP 5111; PROTEASOME ACTIVATOR SUBUNIT-1; IGUP I-5111; ACTIVATOR OF MULTICATALYTIC PROTEASE SUBUNIT 1
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Uniprot ID
Q06323
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Gene Name
PSME1; IFI5111
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human PSME1 (Q06323) (Met1-Tyr249) was expressed with a polyhistidine tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human PSME1 consists of 264 amino acids and predicts a molecular mass of 30.6 KDa. It migrates as an approximately 28-32 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human PA28A / PSME1 Protein (His Tag) SDS-PAGE
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