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  • Proline-rich (Toxin P) peptide

Proline-rich (Toxin P) peptide

Not For Human Use, Lab Use Only.

Cat.#: 313733

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* Buy 1 get 1 free (?) What is TFA?

Special Price 151.80 USD

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Product Information

  • Product Name
    Proline-rich (Toxin P) peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    PYPVYAPPPVVP
  • Sequence
    H-Pro-Tyr-Pro-Val-Tyr-Ala-Pro-Pro-Pro-Val-Val-Pro-OH
  • Length (aa)
    12
  • Peptide Purity (HPLC)
    96.4%
  • Molecular Formula
    C66H94N12O15
  • Molecular Weight
    1295.5
  • Source
    Synthetic
  • Form
    Powder
  • Description

    The proline-rich peptide, referred to as toxin P, is a dodecapeptide with the amino acid sequence PYPVYAPPPVVP and a molecular weight of 1,295.54 Da. It is biosynthesized and secreted by the coral pathogen Vibrio shiloi. This extracellular peptide exhibits a high affinity for binding to zooxanthellae, the symbiotic algae of corals. In aqueous solutions, toxin P has a tendency to aggregate.

    Functionally, toxin P facilitates the rapid transport of ammonia (NH3) into zooxanthellae when ammonium chloride is present. This activity leads to a measurable decrease in the external pH. The peptide's action is characterized by its specific interaction with the algal cells, where it remains bound and mediates the uptake of ammonia, which can disrupt pH gradients.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Banin E, Khare SK, Naider F, Rosenberg E. Proline-rich peptide from the coral pathogen Vibrio shiloi that inhibits photosynthesis of Zooxanthellae. Appl Environ Microbiol. 2001 Apr;67(4):1536-41. doi: 10.1128/AEM.67.4.1536-1541.2001. PMID: 11282602; PMCID: PMC92766.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"