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Product Name
Human alpha-Galactosidase A (His Tag) recombinant protein
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Description
This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.
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Protein name
Prolactin receptor
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Protein short names
ALPHA-D-GALACTOSIDASE A; ALPHA-GAL A; ALPHA-GALACTOSIDASE A; AGS; RP23-26D22.3; AGALSIDASE ALFA; ALPHA-D-GALACTOSIDE GALACTOHYDROLASE 1; GALA; ALPHA-D-GALACTOSIDE GALACTOHYDROLASE; MELIBIASE; GLA
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Uniprot ID
P16471
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Gene Name
PRLR
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human GLA (NP_000940.1) (Met 1-Leu 429) was fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The secreted recombinant human GLA consists of 409 amino acids and has a predicted molecular mass of 46.8 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 50 kDa band.
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Purity
> 97 % as determined by SDS-PAGE
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Validations
Human alpha-Galactosidase A / GLA Protein (His Tag) SDS-PAGE
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