Human NRG4 recombinant protein

Cat.#: 500254

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Product Information

  • Product Name
    Human NRG4 recombinant protein
  • Documents
  • Description
    Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors (By similarity).
  • Protein name
    Pro-neuregulin-4, membrane-bound isoform
  • Protein short names
    HEREGULIN 4; AI552600; PRO-NRG4; PRO-NEUREGULIN-4; HRG4; MEMBRANE-BOUND ISOFORM
  • Uniprot ID
    Q8WWG1
  • Gene Name
    NRG4
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human NRG4 (Q8WWG1) extracellular domain (Pro 2-Phe 62) was expressed and purified, with additional two amino acids (Gly & Pro) at the N-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human NRG4 consists of 63 amino acids and has a calculated molecular mass of 6.7 KDa as estimated in SDS-PAGE under reducing conditions.
  • Purity
    > 92 % as determined by SDS-PAGE
  • Validations

    Human NRG4 Protein SDS-PAGE

    Human NRG4 Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"