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Product Name
Human NRG4 recombinant protein
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Description
Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors (By similarity).
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Protein name
Pro-neuregulin-4, membrane-bound isoform
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Protein short names
HEREGULIN 4; AI552600; PRO-NRG4; PRO-NEUREGULIN-4; HRG4; MEMBRANE-BOUND ISOFORM
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Uniprot ID
Q8WWG1
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Gene Name
NRG4
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human NRG4 (Q8WWG1) extracellular domain (Pro 2-Phe 62) was expressed and purified, with additional two amino acids (Gly & Pro) at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human NRG4 consists of 63 amino acids and has a calculated molecular mass of 6.7 KDa as estimated in SDS-PAGE under reducing conditions.
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Purity
> 92 % as determined by SDS-PAGE
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Validations
Human NRG4 Protein SDS-PAGE
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