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PRAME Polyclonal Antibody

Cat.#: 164886

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Special Price 174.2 USD

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Product Information

  • Product Name
    PRAME Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to PRAME
  • Tested applications
    WB, IF
  • Species reactivity
    Human
  • Alternative names
    PRAME antibody; CT130 antibody; MAPE antibody; OIP-4 antibody; OIP4 antibody; preferentially expressed antigen in melanoma antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PRAME (NP_996839.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
    IF 1:20 - 1:50
  • Validations

    Immunofluorescence - PRAME Polyclonal Antibody

    Immunofluorescence - PRAME Polyclonal Antibody

    Immunofluorescence analysis of U2OS cells using PRAME antibody . Blue: DAPI for nuclear staining.

  • Background
    Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"