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Product Name
Human SerpinB2/PAI-2 (GST Tag) recombinant protein
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Description
Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.
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Protein name
Plasminogen activator inhibitor 2
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Protein short names
PAI; SERPINB2; HST1201; PAI-2; PLANH2; OVALBUMIN; PAI2
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Uniprot ID
P05120
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Gene Name
SERPINB2; PAI2; PLANH2
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the full length of human SERPINB2 (NP_002566.1) (Met 1-Pro 415) was fused with the GST tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human SERPINB2/GST chimera consists of 640 amino acids and predicts a molecular mass of 73 kDa. It migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Activity
Immobilized human GST-SerpinB2 at 10 μg/ml (100 μl/well) can bind biotinylated human uPA-His (Cat:503537), The EC50 of biotinylated human uPA-His (Cat:503537) is 10.24-23.88 ng/ml.
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Validations
Human SerpinB2 / PAI-2 Protein (GST Tag) SDS-PAGE
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