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Product Name
Human PDZD11/PDZK11 (His Tag) recombinant protein
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Description
PDZ domain-containing protein 11, also known as AIPP1a, PISP, PDZD11 and PDZK11, is a cytosolic protein which contains one PDZ (DHR) domain. PDZD11 bears resemblance to members of the MALS / VELIS family of proteins. It contains but one PDZ domain that apparently interacts with the C-terminus of partner proteins. PDZD11 is ubiquitously expressed, and appears to target calcium and copper ATPases to basolateral cell membranes. PDZD11 is a transiently interacting partner of the PMCA b-splice forms that may play a role in their sorting to or from the plasma membrane. Full-length human PDZD11 shares 97% amino acids (aa) identity with mouse PDZD11.
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Protein name
PDZ domain-containing protein 11
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Protein short names
AI854765; RP23-213F21.2; 2700099C19RIK; PISP; PDZK11; PDZD11; 1810012H22RIK; RP13-26D14.3; 2310079D11RIK; AIPP1
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Uniprot ID
Q5EBL8
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Gene Name
PDZD11; AIPP1; PDZK11; PISP; HSPC227; UNQ6486/PRO21335
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human PDZD11 (NP_057568.1) (Asp 2-His 140) was expressed, with a polyhistide tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human PDZD11 consisting of 146 amino acids and has a calculated molecular mass of 16.9 kDa. It migrates as an 18 kDa band in SDS-PAGE under reducing conditions as predicted.
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Purity
> 97 % as determined by SDS-PAGE
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Validations
Human PDZD11 / PDZK11 / PISP Protein (His Tag) SDS-PAGE
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