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Product Name
Human PAPPA2 (His Tag) recombinant protein
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Description
Metalloproteinase which specifically cleaves IGFBP-5. Shows limited proteolysis toward IGFBP-3.
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Protein name
Pappalysin-2
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Protein short names
RP4-774I24.1; PAPP-A2; PLAC3; PAPPALYSIN 2; PAPPE; PAPPA2; PAPP-E
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Uniprot ID
Q9BXP8
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Gene Name
PAPPA2; PLAC3
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human PAPPA2 mature form (NP_064714.2) corresponding to amino acid (Ser 234-Cys 1396) was expressed? with a carboxy-terminal polyhistidine tag.
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Protein Species
Human
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Molecular weight
The secreted recombinant human PAPPA2 consists of 1174 amino acids with the predicted molecular mass of 131 kDa. As a result of glycosylation, rhPAPPA2 migrates as an approximately 170-180 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human PAPPA2 / Pappalysin 2 Protein (His Tag) SDS-PAGE
Related Products / Services
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