• Pape fragment 4 peptide

Pape fragment 4 peptide

Not For Human Use, Lab Use Only.

Cat.#: 301972

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Product Information

  • Product Name
    Pape fragment 4 peptide
  • Documents
  • Sequence Shortening
    APEPAPEAAPEA
  • Sequence
    Ala-Pro-Glu-Pro-Ala-Pro-Glu-Ala-Ala-Pro-Glu-Ala
  • Length (aa)
    12
  • Peptide Purity (HPLC)
    96.42%
  • Molecular Weight
    1149.22
  • Source
    Synthetic
  • Form
    Powder
  • Description

    The Pape fragment 4 peptide is a component identified in the venom of the scorpion Tityus serrulatus. It is derived from the larger Pape protein, which is characterized by repetitive proline- and alanine-rich motifs. This fragment, along with other related peptides, was sequenced using MALDI-TOF-TOF tandem mass spectrometry. The presence of multiple Pape-derived fragments in the venom suggests they are products of post-translational processing.

    These peptides are part of the diverse array of small, non-reticulated molecules found in scorpion venom. Their structural features, including a high proline content, are indicative of the repetitive sequence architecture of the parent Pape protein. The biological role of these specific fragments within the venom composition remains an area for further investigation.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Rates B, Ferraz KK, Borges MH, Richardson M, De Lima ME, Pimenta AM. Tityus serrulatus venom peptidomics: assessing venom peptide diversity. Toxicon. 2008 Oct;52(5):611-8. doi: 10.1016/j.toxicon.2008.07.010. Epub 2008 Jul 31. PMID: 18718845.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"