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Product Name
Human VNN1/Vanin-1 (His Tag) recombinant protein
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Description
Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine.
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Protein name
Pantetheinase
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Protein short names
PANTETHEINE HYDROLASE; PANTETHEINASE; MGC116933; HDLCQ8; V-1; TIFF66; MGC116932; VASCULAR NON-INFLAMMATORY MOLECULE 1; VANNIN 1; MGC116930; VANIN-1; VNN1; MGC116931
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Uniprot ID
O95497
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Gene Name
VNN1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human VNN1 (NP_004657.2) without the propeptide (Met 1-Ser 490) was expressed, fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human VNN1 consists of 480 amino acids and has a predicted molecular mass of 53.7 kDa. It migrates as an approximately 70-75 kDa band in SDS-PAGE under reducing conditions due to glycosylation.
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Purity
> 97 % as determined by SDS-PAGE
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Activity
Measured by its ability to hydrolyze pantetheine to pantothenate and cysteamine. The specific activity is >3000 pmol/min/μg.
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Validations
Human VNN1 / Vanin-1 Protein (His Tag) SDS-PAGE
Related Products / Services
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