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Product Name
Mouse PILRB (Fc Tag) recombinant protein
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Description
Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface. Seems to associate with DAP12 and is a receptor for CD99. May be involved in target cell recognition by natural killer cells and in activation of dendritic cells.
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Protein name
Paired immunoglobulin-like type 2 receptor beta
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Protein short names
ACTIVATING COUNTERPART; PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR BETA; CELL SURFACE RECEPTOR FDFACT; ACTIVATING RECEPTOR PILR-BETA; IMMUNOGLOBULIN-LIKE CELL SURFACE RECEPTOR FDFACT; FDACT; FDFACT; PILRB
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Uniprot ID
Q2YFS2
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Gene Name
Pilrb; Fdfact; Pilrb1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse PILRB1 (Q2YFS2) extracellular domain (Met 1-Gly 193) was fused with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The secreted recombinant mouse PILRB1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 406 amino acids and has a calculated molecular mass of 45.8 kDa. As a result of glycosylation, the apparent molecular mass of rmIL1RAPL1/Fc monomer is approximately 55-60 kDa in SDS-PAGE under reducing conditions.
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Purity
> 85 % as determined by SDS-PAGE
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Validations
Mouse PILRB1 Protein (Fc Tag) SDS-PAGE
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