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Product Name
Human PILR-alpha/PILRA recombinant protein
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Description
Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRA is thought to act as a cellular signaling inhibitory receptor by recruiting cytoplasmic phosphatases like PTPN6/SHP-1 and PTPN11/SHP-2 via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. Receptor for PIANP.
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Protein name
Paired immunoglobulin-like type 2 receptor alpha
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Protein short names
PILR-ALPHA; FDF03; AV021745; PILRA
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Uniprot ID
Q9UKJ1
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Gene Name
PILRA
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human PILRA (AAH17812.1)(Met1-Asp226) was expressed with five amino acids (DDDDK) at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human PILRA comprises 213 amino acids and has a predicted molecular mass of 24.1 kDa. The apparent molecular mass of the protein is approximately 33 kDa in SDS-PAGE under reducing conditions.
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Purity
> 85 % as determined by SDS-PAGE
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Validations
Human PILR-alpha / PILRA Protein SDS-PAGE
Related Products / Services
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