• PAF26 peptide

PAF26 peptide

Not For Human Use, Lab Use Only.

Cat.#: 310126

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Special Price 75.9 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    PAF26 peptide
  • Documents
  • Sequence Shortening
    RKKWFW
  • Sequence
    Arg-Lys-Lys-Trp-Phe-Trp
  • Length (aa)
    6
  • Peptide Purity (HPLC)
    97.8%
  • Source
    Synthetic
  • Form
    Powder
  • Description
    N-terminal acetylation and C-terminal amidation. This cell penetration peptide shows concentration-dependent mechanisms in killing fungi, energy dependent at low concnetration (2-5 uM) but energy indepedent at 20 uM (Muñoz A et al., 2012). A previous entry was replaced Feb 2010. Updated Jan2013. PAF26 has Antifungal, Antibacterial activity. PAF26 was found in Screened from Synthetic Combinatorial Peptide Library.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual:Handling and Storage of Synthetic Peptides
  • References
    • López-garcía B, Pérez-payá E, Marcos JF. Identification of novel hexapeptides bioactive against phytopathogenic fungi through screening of a synthetic peptide combinatorial library. Appl Environ Microbiol. 2002;68(5):2453-60.
  • About TFA salt

    Trifluoroacetic acid (TFA) has a significant impact on peptides due to its role in the peptide synthesis process.

    TFA is essential for the protonation of peptides that lack basic amino acids such as Arginine (Arg), Histidine (His), and Lysine (Lys), or ones that have blocked N-termini. As a result, peptides often contain TFA salts in the final product.

    TFA residues, when present in custom peptides, can cause unpredictable fluctuations in experimental data. At a nanomolar (nM) level, TFA can influence cell experiments, hindering cell growth at low concentrations (as low as 10 nM) and promoting it at higher doses (0.5–7.0 mM). It can also serve as an allosteric regulator on the GlyR of glycine receptors, thereby increasing receptor activity at lower glycine concentrations.

    In an in vivo setting, TFA can trifluoroacetylate amino groups in proteins and phospholipids, inducing potentially unwanted antibody responses. Moreover, TFA can impact structure studies as it affects spectrum absorption.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"