Obestatin peptide
Not For Human Use, Lab Use Only.
Cat.#: 316907
Special Price 225.00 USD
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Product Name
Obestatin peptide
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Documents
Batch to batch variation of the purity
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Sequence Shortening
FNAPFDVGIKLSGAQYQQHGRAL
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Sequence
Phe-Asn-Ala-Pro-Phe-Asp-Val-Gly-Ile-Lys-Leu-Ser-Gly-Ala-Gln-Tyr-Gln-Gln-His-Gly-Arg-Ala-Leu
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Length (aa)
23
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Peptide Purity (HPLC)
95.3%
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Molecular Formula
C114H174N34O31
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Molecular Weight
2516.3
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Source
Synthetic
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Form
Powder
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Description
Obestatin is a peptide hormone encoded by the ghrelin gene. It is derived from the same prohormone precursor as ghrelin through posttranslational processing, which includes cleavage and C-terminal amidation. The mature, amidated form of obestatin is a 23-amino acid peptide. In vitro studies demonstrate that obestatin binds with high affinity to the orphan G protein-coupled receptor GPR39, a receptor belonging to the same subfamily as the ghrelin receptor. This binding initiates intracellular signaling, such as stimulating cyclic adenosine monophosphate production. The peptide is detected in tissues including the stomach, jejunum, and pituitary.
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Storage Guidelines
Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
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References
- Zhang J.V., Ren P.G., Avsian-Kretchmer O., Luo C.W., Rauch R., Klein C., Hsueh A.J.; Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake.; Science 310:996-999(2005).
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About TFA salt
Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.
Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.
Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.
In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.
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Molar Concentration Calculator
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Dilution Calculator
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Percent Concentration Calculator
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
Related Products / Services
• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.
• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"