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  • NY-ESO-1 (87-111) peptide

NY-ESO-1 (87-111) peptide

For research use only. We do not sell to patients.

Cat.#: 319138

Size:
Optional Service: TFA RemovalWhat's this?

Special Price 212.4 USD

Availability: 3 weeks
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Product Information

  • Product Name
    NY-ESO-1 (87-111) peptide
  • Documents
  • Quantity/Unit
    1 Vial
  • Sequence
    H-LLEFYLAMPFATPMEAELARRSLAQ-OH
  • Three letter code
    H-Leu-Leu-Glu-Phe-Tyr-Leu-Ala-Met-Pro-Phe-Ala-Thr-Pro-Met-Glu-Ala-Glu-Leu-Ala-Arg-Arg-Ser-Leu-Ala-Gln-OH
  • Length (aa)
    25
  • Peptide Purity (HPLC)
    95.47
  • Molecular Formula
    C131H206N32O36S2
  • Molecular Weight
    2869.35
  • Source
    Synthetic
  • Additional Information
    This is amino acids 81 to 111 fragment of the NY-ESO-1. The NY-ESO-1 antigen is expressed by many tumors of different histological types (including breast, prostate, lung, and melanoma) and by male germline cells, but not by other normal tissues. NY-ESO-1 encodes MHC class I- and class II-restricted peptides expressed by a diverse range of cancers and recognized by T cells. This peptide is pan-MHC class II-restricted sequence that is capable of binding to multiple HLA-DR and HLA-DP4 molecules, including HLA-DRB1*0101, 0401, 0701, and 1101 and HLA-DPB1*0401 and 0402 molecules.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual:Handling and Storage of Synthetic Peptides
  • References
    • Mandic, M. et al. J. Immunol. 174, 1751 (2005).
  • About TFA salt

    Trifluoroacetic acid (TFA) is a strong acid, which is commonly used to cleave synthesized peptides from solid-phase resins and is also used to improve HPLC performance in the peptide purification step. By default, custom peptides are delivered as lyophilized TFA salts, and can contain as much as 10-45% TFA.

    TFA in custom peptides can cause inexplicable discrepancies in subsequent assay data. For instance, TFA in nM concentrations has been shown to interfere with cellular assays, inhibiting cellular proliferation in some instances, and increasing cell viability in others . It has also been found to be an unintended allosteric modulator of the glycine receptor, GlyR.

    TFA Removal Service is recommended for:

    • Peptides that will be used in cellular assays
    • Peptides that will be used as APIs or in manufactured products
    • For hydrophilic peptides containing numerous basic residues

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"