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Product Name
Recombinant NQO2 protein (His tag)
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Description
This product is a high-quality recombinant protein fragment of Ribosyldihydronicotinamide dehydrogenase [quinone] (NQO2), encompassing residues 1-231. It represents a stable and soluble unit ideal for structural studies and biochemical assays, supporting research in detoxification pathways and enzymatic function.
The full-length NQO2 protein, encoded by the NQO2 gene in Homo sapiens, functions as a quinone reductase involved in detoxification pathways and biosynthetic processes, such as vitamin K-dependent gamma-carboxylation in prothrombin synthesis. It is localized in the cytoplasm, where it facilitates conjugation reactions of hydroquinones, playing a critical role in cellular protection and metabolic regulation.
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Protein name
Ribosyldihydronicotinamide dehydrogenase [quinone]
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Uniprot ID
P16083
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Gene Name
NQO2; NMOR2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-231 aa (P16083) were fused with C-terminal 6His tag.
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Sequence
MAGKKVLIVY AHQEPKSFNG SLKNVAVDEL SRQGCTVTVS DLYAMNLEPR ATDKDITGTL SNPEVFNYGV ETHEAYKQRS LASDITDEQK KVREADLVIF QFPLYWFSVP AILKGWMDRV LCQGFAFDIP GFYDSGLLQG KLALLSVTTG GTAEMYTKTG VNGDSRYFLW PLQHGTLHFC GFKVLAPQIS FAPEIASEEE RKGMVAAWSQ RLQTIWKEEP IPCTAHWHFG QLEHHHHHH
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 26.97 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 28 kDa band.
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Purity
>90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Validations
Recombinant NQO2 protein (His tag) SDS-PAGE
M: Marker; Lane 1: NQO2; Lane 2: BSA
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"