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Product Name
Human NMNAT2 / NMNAT-2 (His Tag) recombinant protein
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Description
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate but with a lower efficiency. Cannot use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity prefers NAD(+), NADH and NaAD as substrates and degrades nicotinic acid adenine dinucleotide phosphate (NHD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+).
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Protein name
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2
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Protein short names
D030041I09RIK; NICOTINAMIDE NUCLEOTIDE ADENYLYLTRANSFERASE 2; AI843915; NMNAT2; NMN ADENYLYLTRANSFERASE 2; PNAT2; NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE 2; NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE 2; RP11-181K3.3; NAMN ADENYLYLTRANSFERASE 1; PYRIDINE NUCLEOTIDE ADENYLYLTRANSFERASE 2; C1ORF15; NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE 1; PNAT1; NAMN ADENYLYLTRANSFERASE 2
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Uniprot ID
Q9BZQ4
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Gene Name
NMNAT2; C1orf15; KIAA0479
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human NMNAT2 (Q9BZQ4-1)(Met1-Gly307) was fused with a polyhistide tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human NMNAT2 consists of 317 amino acids and has a calculated molecular mass of 35.8 kDa. The recombinant protein migrates as an approximately 35 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human NMNAT2 / NMNAT-2 Protein (His Tag) SDS-PAGE
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