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  • Neuropeptide S (1-10) (human)

Neuropeptide S (1-10) (human)

Not For Human Use, Lab Use Only.

Cat.#: 305765

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* Buy 1 get 1 free (?) What is TFA?

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Product Information

  • Product Name
    Neuropeptide S (1-10) (human)
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    SFRNGVGTGM
  • Sequence
    H-Ser-Phe-Arg-Asn-Gly-Val-Gly-Thr-Gly-Met-OH
  • Length (aa)
    10
  • Peptide Purity (HPLC)
    98.2%
  • Molecular Formula
    C42H68N14O14S
  • Molecular Weight
    1025.15
  • CAS No.
    904910-39-0
  • Source
    Synthetic
  • Form
    Powder
  • Description

    Neuropeptide S (1-10) (human) is a decapeptide with the sequence SFRNGVGTGM. It is derived from the precursor protein neuropeptide S (NPS) and is known to modulate various physiological functions, including arousal, anxiety, and food intake. The peptide acts through the neuropeptide S receptor (NPSR), a G protein-coupled receptor, which is widely expressed in the central nervous system. The NPS-NPSR system has been implicated in regulating behavioral responses to stress and in modulating wakefulness.

    Structurally, Neuropeptide S (1-10) (human) features a conserved N-terminal sequence that is critical for receptor binding and activation. The peptide's biological activity is highly dependent on its primary structure, particularly the N-terminal residues, which are essential for its agonist properties. Studies have shown that modifications to the N-terminal region can significantly alter its receptor affinity and functional efficacy.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • A.L.Roth et al., J. Biol. Chem., 281, 20809 (2006)
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

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  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"