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  • Neuropeptide-gamma

Neuropeptide-gamma

Not For Human Use, Lab Use Only.

Cat.#: 300392

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* Buy 1 get 1 free (?) What is TFA?

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Product Information

  • Product Name
    Neuropeptide-gamma
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    DAGYGQISHKRHKTDSFVGLM
  • Sequence
    H-Asp-Ala-Gly-Tyr-Gly-Gln-Ile-Ser-His-Lys-Arg-His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2
  • Length (aa)
    21
  • Peptide Purity (HPLC)
    96.6%
  • Molecular Formula
    C102H160N32O30S
  • Molecular Weight
    2346.6
  • Source
    Synthetic
  • Form
    Powder
  • Description

    Neuropeptide-gamma is a 21-amino acid residue tachykinin peptide derived from the gamma-preprotachykinin A precursor. It shares the conserved carboxyl-terminal sequence -Phe-X-Gly-Leu-Met-NH2 characteristic of tachykinins, which is involved in receptor interaction. In the American alligator (Alligator mississipiensis) brain, neuropeptide-gamma was identified as the most abundant tachykinin, with its primary structure determined as Asp-Ala-Gly-Tyr-Gly-Gln-Ile-Ser-His-Lys-Arg-His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2. This sequence differs from mammalian neuropeptide-gamma by a single substitution of tyrosine for histidine at position four.

    The peptide is a product of alternative splicing of the preprotachykinin A gene transcript. Its presence in high concentration in reptilian brain indicates conservation of tachykinin structures since the divergence of reptiles and mammals, though differential processing of the precursor may occur across species. The structural characterization underscores the molecular conservation within the tachykinin family across vertebrate lineages.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Wang Y, O'harte F, Conlon JM. Structural characterization of tachykinins (neuropeptide gamma, neurokinin A, and substance P) from a reptile, Alligator mississipiensis. Gen Comp Endocrinol. 1992;88(2):277-86.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

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  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"