-
Product Name
Human NRXN3/Neurexin 3 (Fc Tag) recombinant protein
- Documents
-
Description
Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May play a role in angiogenesis (By similarity).
-
Protein name
Neurexin-3-beta
-
Protein short names
NEUREXIN III; MGC176711; NEUREXIN III ALPHA; 9330112C09RIK; NEUREXIN III BETA; C14ORF60; 4933401A11RIK; D12BWG0831E; NEUREXIN III-BETA; KIAA0743; NRXN3; NEUREXIN-3-BETA; NEUREXIN 3; NEUREXIN III-ALPHA; 6332407J11
-
Uniprot ID
Q9HDB5
-
Gene Name
NRXN3; KIAA0743
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the human NRXN3 isoform 2 (NP_620426.2) extracellular domain (Met 1-Thr 357) was fused with the Fc region of human IgG1 at the C-terminus.
-
Protein Species
Human
-
Molecular weight
The secreted recombinant human NRXN3/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 563 amino acids and predictes a molecular mass of 61.6 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh NRXN3/Fc monomer is approximately 75-85 kDa due to glycosylation.
-
Purity
> 95 % as determined by SDS-PAGE
-
Activity
Measured by the ability of the immobilized protein to support the adhesion of C6 Rat brain glial cells. When 5 x 10E4 cells/well are added to NRXN3 coated plates (0.8 μg/ml and 100 μl/well), >30 % will adhere specifically after 60 minutes at 37℃.
-
Validations
Human Neurexin-3-beta / NRXN3 Protein (Fc Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"