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Product Name
H5N1 Neuraminidase (Active) recombinant protein
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Description
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.
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Protein name
Neuraminidase
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Uniprot ID
A7Y9K2
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Gene Name
NA
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Influenza A virus (A/Anhui/1/2005 (H5N1)) neuraminidase (ABU94738.1) (Met 1-Lys 449) was expressed, the cell lysates are collected, and bio-activity was tested. There is an amino acid change from Histidine to Tyrosine (H274Y mutation) in NA / Neuraminidase.
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Protein Species
H5N1
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Molecular weight
The recombinant influenza A H5N1 Neuraminidase comprises 450 amino acids and has a predicted molecular mass of 49.2 kDa.
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Activity
Measured by its ability to cleave a fluorogenic substrate, 2'-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid.
The specific activity is > 60 U
The specific activity is > 300 U
One unit is defined as the amount of enzyme required to cleave 1 nmole of 2'-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid per minute at pH 7.5 at 37℃. -
Validations
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