-
Product Name
Human UNC5A / UNC5H1 (His Tag) recombinant protein
- Documents
-
Description
Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.
-
Protein name
Netrin receptor UNC5A
-
Protein short names
KIAA1976; UNC5H1; MKIAA1976
-
Uniprot ID
Q6ZN44
-
Gene Name
UNC5A; KIAA1976; UNC5H1
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the human UNC5A (NP_588610.2) (Met1-Tyr306) was expressed with a polyhistidine tag at the C-terminus.
-
Protein Species
Human
-
Molecular weight
The recombinant human UNC5A consists 292 amino acids and predicts a molecular mass of 32.7 kDa.
-
Purity
> 95 % as determined by SDS-PAGE.
-
Validations
UNC5A protein SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"