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  • Myosuppressin peptide

Myosuppressin peptide

Not For Human Use, Lab Use Only.

Cat.#: 316960

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* Buy 1 get 1 free (?) What is TFA?

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Product Information

  • Product Name
    Myosuppressin peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    pEDVEHVFLRF-NH2 (pE=Pyroglutamic Acid)
  • Sequence
    H-pGlu-Asp-Val-Glu-His-Val-Phe-Leu-Arg-Phe-NH2
  • Length (aa)
    10
  • Peptide Purity (HPLC)
    96.4%
  • Molecular Formula
    C60H86N16O15
  • Molecular Weight
    1271.42
  • Source
    Synthetic
  • Form
    Powder
  • Description

    Myosuppressin is a neuropeptide belonging to the FMRFamide family, first characterized in insects. In the beetle Zophobas atratus, two myosuppressin peptides were identified: leucomyosuppressin (pEDVDHVFLRFa) and a novel variant designated Zopat-MS-2 (pEDVEHVFLRFa), which differs by a single amino acid substitution at position 4. These peptides were isolated from neuro-endocrine tissues, including the brain and the corpus cardiacum-corpus allatum complex, using techniques such as high-performance liquid chromatography and mass spectrometry.

    Functionally, myosuppressins exhibit myoinhibitory activity on visceral muscles. In Z. atratus, synthetic leucomyosuppressin demonstrated a dose-dependent, reversible inhibitory effect on heart contractile activity. The peptide Zopat-MS-2 also showed cardioinhibitory properties, though it was less potent than leucomyosuppressin. These peptides are part of a conserved group of neuropeptides that modulate muscle contractions in insects.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Marciniak P, Audsley N, Kuczer M, Rosinski G Identification of myotropic neuropeptides from the brain and corpus cardiacum-corpus allatum complex of the beetle, Zophobas atratus J Insect Sci 2010;10:156
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"