Mouse Tnfsf11/Opgl/Rankl/Trance recombinant protein

Mouse Tnfsf11/Opgl/Rankl/Trance recombinant protein

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Mouse tumor necrosis factor ligand superfamily member 11(Tnfsf11) is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is widely expressed in cells including T cells and T cell rich organs, such as thymus and lymph nodes. This cytokine can bind to TNFRSF11B/OPG andTNFRSF11A/RANK. Tnfsf11 is involved in a number of fundamental biological processes such as acting as regulator of interactions between T-cells and dendritic cells, the regulation of the T-cell-dependent immune response and enhancing bone-resorption in humoral hypercalcemia of malignancy. It augments the ability of dendritic cells to stimulate naive T-cell proliferation.

tumor necrosis factor (ligand) superfamily, member 11(Tnfsf11)

Opgl; Rankl; Trance

O35235

E. coli

A DNA sequence encoding the Mouse Tnfsf11/Opgl/Rankl/Trance Gln137-Asp316 is expressed.

Mouse

>95% as determined by SDS-PAGE.