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Product Name
Mouse St6galnac2/Siat7/Siat7b (His tag) recombinant protein
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Description
Alpha‑N‑acetylgalactosaminide alpha ‑2,6‑sialyltransferase 2, is a type II membrane protein localized in the Golgi network and catalyzes 2,6‑sialylation of the Tn antigen. Sialyl‑Tn antigen is highly expressed in several human carcinomas and is associated with carcinoma aggressiveness and poor prognosis. it has been reported that disregulation of this gene is involved in the pathogenesis of IgA nephropathy, a common kidney disease that occurs when antibody IgA accumulates in kidneys (4). The enzyme may also be used to synthesize a cancer vaccine.
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Protein name
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2(St6galnac2)
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Protein short names
Siat7; Siat7b
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Uniprot ID
P70277
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Mouse St6galnac2/Siat7/Siat7b Ser28-Arg373 is expressed with a 6His tag at the C-terminus.
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Protein Species
Mouse
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Purity
>95% as determined by SDS-PAGE.
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Validations
Mouse St6galnac2/Siat7/Siat7b (His tag) recombinant protein
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