Mouse Selplg/Selp1/Selpl (Fc tag) recombinant protein

Mouse Selplg/Selp1/Selpl (Fc tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

P-selectin glycoprotein ligand 1 is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin.

selectin, platelet (p-selectin) ligand(Selplg)

Selp1; Selpl

Q62170

Human Cells

A DNA sequence encoding the Mouse Selplg/Selp1/Selpl Gln42-Cys307 is expressed with a Fc tag at the C-terminus.

Mouse

>95% as determined by SDS-PAGE.