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Product Name
Mouse Flt3/Flk-2/Flt-3 (His tag) recombinant protein
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Description
The Flt-3 receptor, also named Flk-2 and Stk-1, is a member of the class III subfamily of receptor tyrosine kinases.Mouse Flt-3 cDNA encodes a 992 amino acid (aa) residue type I membrane protein with a 27 aa residue signal peptide, a 517 aa extracellular domain with 10 potential N-linked glycosylation sites, a 20 aa residue transmembrane domain and a 428 aa residue cytoplasmic domain. Flt-3 expression has been detected in various tissues, including placenta, gonads, and tissues of nervous and hematopoietic origin. Among hematopoietic cells, the expression of Flt-3 was found to be restricted to the highly enriched stem/progenitor cell populations. The ligand for Flt-3 (FL) has been identified to be a transmembrane protein with structural homology to M-CSF and SCF.
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Protein name
FMS-like tyrosine kinase 3(Flt3)
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Protein short names
Flk-2; Flt-3
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Uniprot ID
Q00342
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Mouse Flt3/Flk-2/Flt-3 Asn28-Ser544 is expressed with a Fc tag at the C-terminus.
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Protein Species
Mouse
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Purity
>95% as determined by SDS-PAGE.
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Validations
Mouse Flt3/Flk-2/Flt-3 (His tag) recombinant protein
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