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Product Name
Mouse EPHA3/Eph Receptor A3 (aa 569-984) recombinant protein
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Description
EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 gene encodes a protein that binds ephrin-A ligands. EPHA3 is involved in the retinotectal mapping of neurons. It may also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.
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Protein short names
ETK1; AW492086; TYROSINE-PROTEIN KINASE RECEPTOR ETK1; EK4; HEK; EPHRIN TYPE-A RECEPTOR 3; MEK4; CEK4; ETK; EPHA3; HUMAN EMBRYO KINASE 1; EPH-LIKE TYROSINE KINASE 1; END3; EPH-LIKE KINASE 4; TYRO4; TYRO4 PROTEIN TYROSINE KINASE; HEK4; EPH RECEPTOR A3; TYROSINE-PROTEIN KINASE TYRO4
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse EPHA3 (EDK98238.1) (Gly569-Val984) was expressed with two additional amino acids (Gly & Pro ) at the N-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse EPHA3 consists of 418 amino acids and has a calculated molecular mass of 46.6 kDa. The recombinant protein migrates as an approximately 44 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 85 % as determined by SDS-PAGE
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Activity
Kinase activity untested
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Validations
Mouse EphA3 Protein (aa 569-984) SDS-PAGE
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