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Product Name
Mouse Cxcl9/Mig/Scyb9 recombinant protein
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Description
Chemokine (C-X-C motif) ligand 9 (CXCL9, MIG), is a small cytokine belonging to the CXC chemokine family. CXCL9 functions as one of the three ligands of chemokine receptor CXCR3 which is a G protein-coupled receptor found predominantly on T cells. It together with CXCL10 and CXCL11, may activate CXCR3 by binding to it. CXCL9 serves as a cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. It has been observed that tumour endothelial cells secrete high levels of CXCL9 in all, and CXCL10 in most melanoma metastases. it plays an important role in CD4+ T lymphocyte recruitment and development of CAV, MOMA-2+ macrophages are the predominant recipient-derived source of CXCL9, and recipient CD4 lymphocytes are necessary for sustained CXCL9 production and CAV development in this model.
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Protein name
chemokine (C-X-C motif) ligand 9(Cxcl9)
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Protein short names
Mig; Scyb9
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Uniprot ID
P18340
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Mouse Cxcl9/Mig/Scyb9 Thr22Thr126 is expressed.
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Protein Species
Mouse
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Purity
>95% as determined by SDS-PAGE.
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Validations
Mouse Cxcl9/Mig/Scyb9 recombinant protein
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