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Product Name
Mouse CREG1 (His Tag) recombinant protein
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Description
CREG1 belongs to the CREG family. It is a adenovirus E1A protein which both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. Thus it may contribute to the transcriptional control of cell growth and differentiation. The transcriptional control activity of cell growth requires interaction with IGF2R. CREG1 also antagonizes transcriptional activation and cellular transformation by E1A. It shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. CREG1 gene may contribute to the transcriptional control of cell growth and differentiation.
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Protein name
Protein CREG1
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Protein short names
PROTEIN CREG1; AA755314; CREG1; CREG; CELLULAR REPRESSOR OF E1A-STIMULATED GENES 1; UNQ727/PRO1409
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Uniprot ID
O88668
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Gene Name
Creg1; Creg
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse CREG (O88668) (Met1-Gln220) was expressed with a C-terminal polyhistidine tag.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse CREG comprises 200 amino acids and has a predicted molecular mass of 22.9 kDa. The apparent molecular mass of the protein is approximately 28-32 kDa in SDS-PAGE under reducing conditions due to glycosylation.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Mouse CREG / CREG1 Protein (His Tag) SDS-PAGE
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