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Product Name
Mouse CHL1/LICAM2/CALL (Fc Tag) recombinant protein
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Description
Neural cell adhesion molecule L1-like protein, also known as close homolog of L1 (CHL1) is the prototypic member of the CTF / NF-1 family of transcription factors that serve as a novel calcium signaling pathway-responsive transcription factor and is considered as a member of the largest ctf complementation group, consisting of 30 of 126 ctf mutants isolated. CHL1 is a cell adhesion molecule highly related to L1. It contains structure plan of six extracellular C2-type immunoglobulin (Ig) domains followed by five fibronectin type? domains linked by a single membrane-spanning region to a short cytoplasmic domain. The extracellular portion of CHL1 is higyly glycosylated and involved them in hemophilic disease.
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Protein short names
CHL1; LICAM2; L1CAM2; MGC132578; AI465420; A530023M13RIK; CHL-1; FLJ44930; CALL
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse CHL1 (Met1-Gln1027) was expressed with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse CHL1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 1244 amino acids and has a predicted molecular mass of 139.4 kDa. The apparent molecular mass of the protein is approximately 140 kDa in SDS-PAGE under reducing conditions due to glycosylation.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Mouse CHL-1 Protein (Fc Tag) SDS-PAGE
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