Mouse CD200R4 (Fc Tag) recombinant protein

Cat.#: 503603

Size:

Special Price 621.5 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Mouse CD200R4 (Fc Tag) recombinant protein
  • Documents
  • Description
    Mouse Cell surface glycoprotein CD200 receptor 4, also known as Cell surface glycoprotein OX2 receptor 4, CD200 cell surface glycoprotein receptor-like 4, CD200RLa, and CD200R4, is a single-pass type I  membrane protein which belongs to the CD200R family. CD200 (OX2) is a cell surface glycoprotein that interacts with a structurally related receptor (CD200R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. In mouse there are up to five genes related to CD200R with conflicting data as to whether they bind CD200. CD200R4 contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. CD200R4 is highly expressed in monocytes, NK cells and a subset of NKT cells. It is weakly expressed in granulocytes and B cells (at protein level). CD200R4 is also expressed in brain, lung, testis, thymus, intestine and uterus. and in bone marrow derived-macrophage and dendritic cells and mast cells. CD200R4 is involved in the recruitment or surface expression of the TYROBP receptor.
  • Protein name
    Cell surface glycoprotein CD200 receptor 4
  • Protein short names
    MCD200RLA; F630107N04RIK; CD200R4
  • Uniprot ID
    Q6XJV4
  • Gene Name
    Cd200r4
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the extracellular domain of mouse CD200R4 (NP_997127.1) (Met 1-Thr 241) was fused with the Fc region of human IgG1 at the C-terminus.
  • Protein Species
    Mouse
  • Molecular weight
    The recombinant mouse CD200R4/Fc is a disulfide-linked homodimer. The reduced monomer comprises 457 amino acids and has a predicted molecular mass of 50.6 kDa. As a result of glycosylation, the apparent molecular mass of rm CD200R4/Fc monomer is approximately 80-90 kDa in SDS-PAGE under reducing conditions.
  • Purity
    > 94 % as determined by SDS-PAGE
  • Validations

    Mouse CD200R4 / CD200 Receptor 4 / CD200RLa Protein (Fc Tag) SDS-PAGE

    Mouse CD200R4 / CD200 Receptor 4 / CD200RLa Protein (Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"