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Product Name
Mouse Ccl21a/Scya21/Scya21a recombinant protein
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Description
C-C Motif Chemokine 21a (CCL21a) is a small secreted cytokine that belongs to the intercrine beta (CC chemokine) family. Mouse CCL21 cDNA encodes a 133 amino acid residue protein with a 23 residue signal peptide that is cleaved to generate the 110 residue mature protein. Mouse CCL21 has three forms while CCL21a has Ser-65. CCL21 elicits its effects by binding to a cell surface chemokine receptor known as CCR7 and CXCR3. Mouse CCL21 inhibits hemopoiesis and stimulates chemotaxis. It has chemotactic function in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Mouse CCL21 shows preferential activity towards naive T-cells and may play a role in mediating homing of lymphocytes to secondary lymphoid organs.
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Protein name
predicted gene 1987(Gm1987)
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Protein short names
Scya21; Scya21a
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Uniprot ID
P84444
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Mouse Ccl21a/Scya21/Scya21a Ser24-Gly133 is expressed.
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Protein Species
Mouse
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Purity
>95% as determined by SDS-PAGE.
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Validations
Mouse Ccl21a/Scya21/Scya21a recombinant protein
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