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Product Name
Mouse Alpha 1 Antitrypsin / Serpin A1a (Fc Tag) recombinant protein
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Protein short names
SERINE (OR CYSTEINE) PEPTIDASE INHIBITOR; AAT2; ALPHA-1-ANTITRYPSIN 2; ALPHA-1-ANTITRYPSIN 1-1; MEMBER 1A; DOM1; SPI1-3; SERINE PROTEASE INHIBITOR 1-1; SERINE (OR CYSTEINE) PROTEINASE INHIBITOR; ALPHA-1 PROTEASE INHIBITOR 1; PI1; AAT; SPI1-1; CLADE A; ALPHA-1-ANTIPROTEINASE; SERINE PROTEASE INHIBITOR A1A; SERPINA1A; SERPIN A1A; AAT-2
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse Serpina1a (XP_003945711.1) (Met1-Lys413) was expressed with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse Serpina1a comprises 627 amino acids and has a predicted molecular mass of 70.2 kDa. The apparent molecular mass of the protein is approximately 67-77 kDa in SDS-PAGE under reducing conditions due to glycosylation.
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Purity
> 95 % as determined by SDS-PAGE
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Activity
Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate,Mca-Arg-Pro-Lys-Pro-Val-Glu-Nval-Trp-Arg-Lys (DNP)-NH2.
The IC50 value is < 1 nM. -
Validations
Mouse Alpha 1 Antitrypsin / SerpinA1a Protein (Fc Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"