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Product Name
Mouse ACE2 Protein (Fc Tag)
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Description
The S protein of the SARS-COV-2 binds to the receptor of ACE2 protein on cell membrane, and then infects human respiratory epithelial cells. The observation under electron microscope confirmed the molecular mechanism of the infection. The specific binding to the receptor of ACE2 molecule is the receptor binding domain (RBD)located on the S1 Subunit of the S protein.
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Uniprot ID
Q8R0I0
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse ACE2 isoform 1 (Q8R0I0-1) extracellular domain (Met 1-Thr 740) was fused with the C-terminal Fc tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The secreted recombinant mouse ACE2/Fc is a disulfide-linked homodimer. The reduced monomer has a predicted molecular mass of 112 kDa. As a result of glycosylation, it migrates as an approximately 130 kDa band in SDS-PAGE under reducing conditions.
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Purity
>90%
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Validations
Mouse ACE2 Protein (Fc Tag)
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