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Product Name
MEST antibody
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Description
MEST Mouse Monoclonal antibody. Positive IHC detected in human prostate cancer tissue. Positive WB detected in PC-3 cells. Observed molecular weight by Western-blot: 34 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse; other species not tested.
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Alternative names
DKFZp686L18234 antibody; MEST antibody; PEG1 antibody
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Isotype
Mouse IgG2a
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Preparation
This antibody was obtained by immunization of MEST recombinant protein (Accession Number: NM_002402). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:50-1:500
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Validations
PC-3 cells were subjected to SDS PAGE followed by western blot with Catalog No:107423(MEST antibody) at dilution of 1:1000
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Background
MEST(Mesoderm-specific transcript homolog protein) is also named as PEG1 and belongs to the AB hydrolase superfamily. The gene is a imprinting gene, which is associated with growth of mesodermal origin cells(PMID:20339302) and plays important roles in embryo development(PMID:21375506). It is also a novel regulator of Wnt/CTNNB signalling during adipogenic differentiation(PMID:21375506). It has 3 isoforms produced by alternative splicing and the full length protein has a glycosylation site.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"