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Product Name
Human MEP1B / Meprin beta (His Tag) recombinant protein
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Description
Membrane metallopeptidase that sheds many membrane-bound proteins. Known substrates include: FGF19, VGFA, IL1B, IL18, procollagen I and III, E-cadherin, KLK7, gastrin, ADAM10, tenascin-C. The presence of several pro-inflammatory cytokine among substrates implicate MEP1B in inflammation. It is also involved in tissue remodeling due to its capability to degrade extracellular matrix components.
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Protein name
Meprin A subunit beta
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Protein short names
MEP-1B
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Uniprot ID
Q16820
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Gene Name
MEP1B
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human MEP1B (NP_005916.2) (Met1-Thr652) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human MEP1B consists 641 amino acids and predicts a molecular mass of 73 kDa.
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Purity
> 95 % as determined by SDS-PAGE.
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Validations
Human MEP1B / Meprin beta Protein (His Tag)
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