MEPE antibody

Cat.#: 112658

Size:

Special Price 239.0 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    MEPE antibody
  • Documents
  • Description
    MEPE Rabbit Polyclonal antibody. Positive WB detected in HepG2 cells, A2780 cells, HeLa cells. Observed molecular weight by Western-blot: 43kd,98kd
  • Tested applications
    ELISA, WB
  • Species reactivity
    human; other species not tested.
  • Alternative names
    MEPE antibody; Osteoblast/osteOCyte factor 45 antibody; OF45 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Peptide (Accession Number: NM_020203). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:1000-1:10000

  • Validations

    HepG2 cells were subjected to SDS PAGE followed by western blot with Catalog No:112658(MEPE antibody) at dilution of 1:600

    HepG2 cells were subjected to SDS PAGE followed by western blot with Catalog No:112658(MEPE antibody) at dilution of 1:600

  • Background
    Matrix extracellular phosphoglycoprotein (MEPE), also known as osteoblast/osteocyte factor 45 (OF45), is amember of the small integrin-binding ligand N-linked glycopro-tein (SIBLING) family (PMID: 12952171). MEPE promotes renal phosphate excretion and modulates mineralization (PMID: 22582013). It can be phosphorylated by secreted protein kinases. (PMID: 14962809). MEPE is expressed in osteoblasts, osteocytes and odontoblasts, and the expression has also been reported in numerous human tumor cell lines (PMID: 14962809; 20145617). It is a 525-amino acid protein with a calculated molecular weight of 58 kDa. This antibody raised against a synthetic peptide (CTHGRKYHYVPHRQNNSTR) detects a major band (43 kDa) and two minor bands (98 kDa and 34 kDa).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"