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Product Name
Human MRAP / FLAP (Fc Tag) recombinant protein
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Description
Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R). Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH). May be involved in the intracellular trafficking pathways in adipocyte cells.
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Protein name
Melanocortin-2 receptor accessory protein
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Protein short names
FALP; ORF61; C21ORF61; B27; GCCD2; 1110025G12RIK; FGD2; C21ORF61; FALP
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Uniprot ID
Q8TCY5
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Gene Name
MRAP; C21orf61; FALP
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human MRAP (NP_848932.1) (Tyr59-Ser172) was expressed with the Fc region of human IgG1 at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human MRAP consists 374 amino acids and predicts a molecular mass of 40.9 kDa.
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Purity
> (18.4+72.1) % as determined by SDS-PAGE.
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Validations
MRAP protein SDS-PAGE
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