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  • Mastoparan-V1 peptide

Mastoparan-V1 peptide

Not For Human Use, Lab Use Only.

Cat.#: 314107

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Product Information

  • Product Name
    Mastoparan-V1 peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    INWKKIKSIIKAAMN
  • Sequence
    H-Ile-Asn-Trp-Lys-Lys-Ile-Lys-Ser-Ile-Ile-Lys-Ala-Ala-Met-Asn-OH
  • Length (aa)
    15
  • Peptide Purity (HPLC)
    97.55%
  • Molecular Formula
    C81H140N22O19S
  • Molecular Weight
    1758.21
  • Source
    Synthetic
  • Form
    Powder
  • Description

    Mastoparan-V1 is a cationic tetradecapeptide isolated from the venom sac extract of the yellow jacket Vespula vulgaris. Its primary amino acid sequence is INWKKIKSIIKAAMN. This peptide belongs to the mastoparan family, which are basic peptides known for their mast cell degranulating activity.

    In biological studies, Mastoparan-V1 can stimulate the release of specific mediators, such as prostaglandin E2, from murine peritoneal cells and macrophages. The peptide exhibits synergistic inflammatory activity with another venom component, phospholipase A1. Its mechanism of action is associated with interactions with cell membranes and the induction of secretory responses in various cell types.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • King TP, Jim SY, Wittkowski KM. Inflammatory role of two venom components of yellow jackets (Vespula vulgaris): a mast cell degranulating peptide mastoparan and phospholipase A1. Int Arch Allergy Immunol. 2003 May;131(1):25-32. doi: 10.1159/000070431. PMID: 12759486.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"