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Product Name
Human MBL-2 / MBL recombinant protein
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Description
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.
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Protein name
Mannose-binding protein C
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Protein short names
MBL2; MGC116833; MGC116832; HSMBPC; L-MBP; MBL2D; MBP1; COLEC1; MBPD; MBL; MBL-C; MBP; MBP-C
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Uniprot ID
P11226
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Gene Name
MBL2; COLEC1; MBL
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Source/Expression Host
CHO Stable Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human MBL (NP_000233.1) (Met1-Ile 248) was expressed.
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Protein Species
Human
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Molecular weight
The recombinant human MBL consists of 228 amino acids and predicts a molecular mass of 24 KDa. It migrates as an approximately 31 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human MBL2 / MBL / COLEC1 Protein SDS-PAGE
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