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Product Name
RSV RSV-G / Glycoprotein G (His Tag)
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Description
Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities (By similarity).
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Protein name
Major surface glycoprotein G
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Protein short names
RESPIRATORY SYNCYTIAL VIRUS; ATTACHMENT GLYCOPROTEIN (G); PROTEIN G; RSVGP07; G
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Uniprot ID
O36633
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Gene Name
G
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the extracellular domain of human RSV strain B1 glycoprotein G (O36633-1) (His 67-Ala 299) was fused with a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus.
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Protein Species
RSV
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Molecular weight
The secreted recombinant human RSV strain B1 glycoprotein G comprises 244 amino acids with a predicted molecular mass of 27 kDa. As a result of highly glycosylation, the apparent molecular mass of the recombinant protein is approximately 80-90 kDa in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human RSV (B1) glycoprotein G / RSV-G Protein (His Tag) SDS-PAGE
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