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Product Name
RSV RSV-G / Glycoprotein G (His Tag)
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Description
Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities (By similarity).
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Protein name
Major surface glycoprotein G
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Protein short names
RESPIRATORY SYNCYTIAL VIRUS; ATTACHMENT GLYCOPROTEIN (G); PROTEIN G; RSVGP07; G
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Uniprot ID
P27022
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Gene Name
G
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the glycoprotein G extracellular domain (Asn 66-Arg297) of human respiratory syncytial virus A (93% homologous with strain rsb1734) (P27022-1) was expressed, with a C-terminal polyhistidine tag.
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Protein Species
RSV
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Molecular weight
The secreted recombinant human RSV-G comprises 242 amino acids and has a predicted molecular mass of 26.3 kDa. As a result of glycosylation, the apparent molecular mass of RSV protein G is approximately 40-55 kDa in SDS-PAGE under reducing conditions.
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Purity
> 92 % as determined by SDS-PAGE
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Validations
Human RSV (A, rsb1734) glycoprotein G / RSV-G Protein (93% Homology) (His Tag) SDS-PAGE
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