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Product Name
Mouse LY-96 / ESOP-1 (Fc Tag) recombinant protein
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Description
Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS (By similarity).
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Protein name
Lymphocyte antigen 96
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Protein short names
LYMPHOCYTE ANTIGEN 96; ESOP-1; MD-2; MD2; LY-96; PROTEIN MD-2; LY96; MYELOID DIFFERENTIATION PROTEIN-2
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Uniprot ID
Q9JHF9
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Gene Name
Ly96; Esop1; Md2
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse LY96 (Q9JHF9) (Met1-Asn160) was expressed with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse LY96/Fc is a disulfide-linked homodimer. The reduced monomer comprises 383 amino acids and has a predicted molecular mass of 43.4 kDa. The apparent molecular mass of the protein is approximately 47 kDa in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Mouse LY-96 / ESOP-1 Protein (Fc Tag) SDS-PAGE
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