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Product Name
LSM11 Polyclonal Antibody
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Description
Polyclonal antibody to LSM11
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Tested applications
IF
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Species reactivity
Human
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Alternative names
LSM11 antibody; LSM11, U7 small nuclear RNA associated antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 131-360 of human LSM11 (NP_775762.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
IF 1:50 - 1:200
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Validations
Immunofluorescence - LSM11 Polyclonal Antibody
Immunofluorescence analysis of U2OS cells using LSM11 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
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Background
Component of the U7 snRNP complex that is involved in the histone 3'-end pre-mRNA processing (By similarity). Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to the Sm-binding site of U7 snRNA.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"