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Product Name
LRRC52 antibody
- Documents
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Description
LRRC52 Rabbit Polyclonal antibody. Positive WB detected in mouse skeletal muscle tissue. Observed molecular weight by Western-blot: 45 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
FLJ25811 antibody; LRRC52 antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of LRRC52 recombinant protein (Accession Number: NM_001005214). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with Catalog No:112336(LRRC52 Antibody) at dilution of 1:600
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Background
LRRC52 (leucine-rich repeat-containing protein 52) belongs to the gamma family of the BK channel accessory subunits, which potentially regulate the channel’s gating properties (PMID: 22547800). It is dominantly expressed in testis and skeletal muscle, with much lower expression in several other tissues including placenta, kidney, lung, and some glands. LRRC52 has been reported as a Slo3 auxiliary subunit that helps define the specific alkalization dependence of KSper activation. LRRC52 has a calcular molecular weight of 35 kDa. This polyclonal antibody raised against 24-244aa of human LRRC52 reveals a band of 45 kDa, which is consistent with the molecular weight of glycosylated form of LRRC52 (PMID: 22084117).
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