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Product Name
LOX Polyclonal Antibody
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Description
Polyclonal antibody to LOX
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Tested applications
WB, IHC
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Species reactivity
Human, Mouse, Rat
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Alternative names
LOX antibody; AAT10 antibody; lysyl oxidase antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human LOX
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
IHC 1:50 - 1:200 -
Validations
Western blot - LOX Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using LOX antibody at 1:500 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit ._Exposure time: 90s.
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Background
Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture (By similarity).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"